AGOMELATINE (Melitor, Thymanax) is the first melatonergic antidepressant that is used to treat depressions of different origins, to prevent depression returning and to improve sleep patterns. The active component of Agomelatine is agomelatine which stimulates melatonin secretion by acting upon melatonin receptors. Agomelatine also acts as serotonin antagonist which results in the release of norepinephrine and dopamine (it does not affect serotonin levels). Due to its action upon melatonin receptors, agomelatine improves overall sleep quality without daytime sedation. Agomelatine is considered to be well tolerated, has no effect on body weight and sexual function, exhibits no discontinuation syndrome.
Treat Major Depression in Adults Including Prevention of Relapse.
Remove Sleep Disorders.
GUARANTEE & EXPIRY DATE
100% Original pharmacy product from Russian Ozon or another similar manufacturer.
Agomelatine is a novel agent with melatonin-agonist and 5HT2c-antagonist activity. As the first antidepressant to be an agonist at melatonergic MT1 and MT2 receptors and an antagonist at serotonergic 5HT2C receptors, it uniquely regulates disturbed circadian rhythms which results in improving of sleep patterns. Acting as serotonin antagonist Agomelatine induces the release of norepinephrine and dopamine – two critical neurotransmitters that regulate areas of the brain that are involved in the control of mood. This is believed to help relieve the symptoms of depression. Further read: https://en.wikipedia.org/wiki/Agomelatine
INSTRUCTIONS & DOSAGE
Active substance: agomelatine 25mg.
Excipients: lactose monohydrate, magnesium stearate, maize starch, povidone, colloidal silicon dioxide, carboximetilkrahmal sodium, stearic acid.
Agomelatine should be taken orally at bedtime. Recommended daily dose is 25mg. If there are no noticeable improvements the dose may be increased to 50mg/day.
Store in dry place at room temperature. Do not exceed storage temperature higher than 25 degrees Celcius. Keep away from direct sunlight. Keep locked and away from children.
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