NALTREXONE (ReVia, Vivitrol) is an opioid receptor antagonist. It is used for the treatment of alcohol dependence by blocking the euphoric effects and decreasing the desire to take alcohol again. It is also used as part of a complex therapy for drug abuse. Naltrexone effectively minimizes withdrawal symptomatology. It was found out that using of naltrexone in a lower dose at bedtime, improves the functioning of the body’s immune system.
Prevention the Effect of Exogenous Opioids in Opioid Dependent Patients
Complex Treatment of Alcohol Dependence
GUARANTEE & EXPIRY DATE
100% Original pharmacy product from Russian Moscow Pharmaceutical Factory or another manufacturer. Photo is for illustration purpose and may differ from actual packaging.
Naltrexone is a derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone. It competitively binds to mc, κ, δ and μ receptors in the CNS and may block the effects of endogenous opioids, thus leading to the antagonization of most of the subjective and objective effects of opiates. The metabolite of naltrexone, 6-β-naltrexol, is also an opiate antagonist and reduces the activity of the drug. Further read: https://https://en.wikipedia.org/wiki/Naltrexone.
INSTRUCTIONS & DOSAGE
Active substance: Naltrexone hydrochloride 50mg
The drug is orally administered only after the reduction of abstinence syndrome and detoxication.
The treatment is started in 7-10 days of abstinence under supervision in a special clinic or treatment center.
Treatment of alcohol dependence: the usual dose is 50mg/day; 12-week course of treatment prevents relapse for the next 6 months (treatment effectiveness depends on the agreement of the patient).
Treatment of opioid dependence: the treatment is started in 7-10 days of abstinence, proved by laboratory testing, including toxicological screening. Ensure that the signs and symptoms of withdrawal and abstinence have subsided. After taking the initial dose of 25mg a patient has to stay under control for an hour. If there is no abstinence syndrome – the dose is increased up to 50mg/day.
Alternative schemes of treatment:
1. 50mg every weekday and 100mg on Saturdays
2. 100mg in a day
3. 150mg in 2 days
4. 100mg on Monday, 100mg on Wensday and 150mg on Friday
Note that these schemes of treatment increases the risk of hepatotoxity. The therapy is administered individually.
Store in dry place at room temperature. Do not exceed storage temperature higher than 25 degrees Celcius. Keep away from direct sunlight. Keep locked and away from children.