Memantine 200 tabs/pack

MEMANTINE is used to treat, slow down and prevent the development of moderate to severe Alzheimer’s disease. Off-label use of Memantine Canon includes treating psychiatric conditions in children and adolescents, such as attention deficit hyperactivity disorder, major depressive disorder and bipolar disorder, autism spectrum disorder. It also improves cognitive functions and memory in opioid-dependent patients. It works by regulating receptors in the brain and reducing specific activity that leads to the development of cognitive impairments.

USES
Treat Moderate to Severe Alzheimer’s Disease
Eliminate Opioid Withdrawal Symptoms
Restore and Improve Cognition, Learning, Memory
Eradicate Cerebral and Spinal Spastic Syndrome Caused by Traumatic Brain Injury, Multiple Sclerosis, Stroke

GUARANTEE & EXPIRY DATE
100% Original generic from various Indian pharmaceutical companies.

DESCRIPTION
Memantine is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonists. By selective binding to the NMDA receptors Memantine blocks the excitotoxic effects, excitation and overstimulation associated with abnormal glutamatergic transmission, thus preventing damage to those receptors, while allowing physiological transmission associated with normal cell functioning. Regulating excessive glutamate activity Memantine prevents disturbed glutamate neurotransmission that leads to the development of cognitive and psychiatric disorders.

PACKAGING & DOSAGE
Active substance:
memantine hydrochloride – 10mg

Excipients:
colloidal silica (Aerosil) – 3mg, calcium hydrogen phosphate dihydrate – 50.4mg, croscarmellose sodium (primelloza) – 3mg, lactose monohydrate – 136mg, Magnesium stearate – 1.6 mg, Povidone – 6mg.

The composition of the coating film:
selekoat AQ-02003 (hypromellose – 3.6mg, macrogol – 6000 – 1.2mg, titanium dioxide – 1.2mg) – 6 mg.

Recommendations for use:
The drug should be taken oraly with meals in the morning. The initial dose for the 1st week is 10mg/day, 2nd week – 20mg/day, 3rd week – 20-30mg/day. If it is required – increase the dose for 10mg every week till the maximum 30mg/day.

STORAGE
Store in dry place at room temperature. Do not exceed storage temperature higher than 25 degrees Celcius. Keep away from direct sunlight. Keep locked and away from children.