Divaza 100 tabs/pack

DIVAZA is effective in improving cognitive functions, reducing signs of mental and physical asthenia, increasing activity and motivation, resolving asthenic symptoms of the autonomic nervous system and restoring psychic performance, alleviating headache and vertigo, decreasing emotional lability, anxiety and depression, and ameliorating sleep disturbances. It has good tolerability, does not cause side effects and is compatible with any other medications that may be used concomitantly. Divaza is available in a convenient form, i.e. orally disintegrating tablets.

USES
Mild to moderate cognitive disorders.
Neurodegenerative and cerebrovascular disorders.
Antihypoxant and antioxidant activity.
Reduction of the lipid peroxidation process.

GUARANTEE & EXPIRY DATE
100% original from Russian pharmaceutical company Materia Medica Holding. Photos of the product are for illustration purpose only and may vary according to the manufacturer.

DESCRIPTION
Antibodies to the brain-specific protein S-100 have an antioxidant, antihypoxic, neuroprotective, anxiolytic effect. The functional activity of the S-100 protein is modified, which implements information and metabolic processes in the brain. They have a membranotropic effect, causing a decrease in amplitude and suppression of the generation of the action potential; modulate synaptic plasticity in the limbic structures of the brain, hippocampus, reticular formation; contribute to enhancing the inhibitory effects of GABA in the central nervous system. The properties of the sigma 1 receptor agonist in vitro are exhibited.

Inhibit lipid peroxidation processes. They have a normalizing effect on the integrative activity of the brain, which is manifested by a wide range of balanced psychopharmacological effects: antidepressant, anxiolytic, neuroprotective, antiasthenic, antiamnestic.

Antibodies to endothelial NO synthase increase the activity of the enzyme endothelial NO synthase, restore endothelial production of nitric oxide (NO), eliminate endothelial dysfunction, have endothelial protective effect, and affect NO-dependent vasodilation. The stimulating effect of Divaza on reparative processes in the focus of ischemic brain damage has been experimentally shown.

The joint use of the drug components is accompanied by an increase in the neuroprotective activity of antibodies to the S-100 protein, an increase in the vegetative-stabilizing effect, normalization of the vegetative status, the synergistic effect of both components on neuronal plasticity, and, as a result, increased brain resistance to toxic effects; improves integrative activity and restores interhemispheric connections of the brain, helps to eliminate cognitive impairment, stimulates reparative processes and accelerates the restoration of central nervous system functions, increases mental performance, restores learning and memory processes, normalizes somatovegetative manifestations, increases cerebral blood flow.

As well as its constituent components, Divaza does not have a sedative and muscle relaxant effect, does not cause addiction and addiction.

PACKAGING
DIVAZA comes in the form of tablets for oral use.

Active ingredienst:
Antibodies to the brain-specific protein S-100 affinity purified – 6 mg.
Antibodies to endothelial NO synthase affinity purified – 6 mg.

Excipients:
Lactose monohydrate, microcrystalline cellulose, magnesium stearate.

DOSAGE
Orally, keep in mouth until completely dissolved. 1 to 2 tablets 3 times a day at regular intervals, 2 hours before or after meal. Depending on the severity of the condition in the acute period, the frequency of administration can be increased up to 4-6 times a day.

Usual course of intake 2-3 months. With severe organic lesions of the central nervous system the duration of course therapy can reach 4-6 months.

PRECAUTIONS
Increased individual sensitivity to the components of the drug.
Divaza is not recommended for use in patients under the age of 18 years due to insufficient data on efficacy and safety for this age.
Lactase deficiency, lactose intolerance, glucose-galactose malabsorption.

SIDE EFFECTS
Possible reactions of increased individual sensitivity to the components of the drug.

STORAGE
Store in dry place at room temperature. Do not exceed storage temperature higher than 25 degrees Celcius. Keep away from direct sunlight. Keep locked and away from children.